Ethylene diamine tetraacetic acid (EDTA) chelation was first used in the 1940s for lead poisoning and was approved by the U.S. Food and Drug Administration (FDA) for this use in 1953.
Some clinicians who used EDTA for lead poisoning have reported possible side benefits in people with heart disorders. However, there is conflicting data on this use.
Evidence is lacking in support of the use of chelation therapy for clogged arteries, diabetic kidney disease, eye disorders, ovarian cancer, scleroderma (the build-up of scar tissue on the skin), and hexachlorobenzene toxicity. It has also been used to treat kidney dysfunction.
EDTA chelation therapy is rejected by the conventional medical community, including the American Medical Association, American Hospital Association, National Institutes of Health, and Food and Drug Administration, due to a lack of scientific evidence.
In 1998, the U.S. Federal Trade Commission (FTC) secured a consent agreement barring the American College for Advancement in Medicine (ACAM), the main organization that supports chelation therapy, from making unproven advertising claims that chelation therapy is effective against any other disease of the circulatory system.
CaEDTA, calcium disodium versenate, calcium ethylenediaminetetra-acetate, calcium versenate, CaNa (2) EDTA, CaNa2 ethylenediamine tetraacetic acid, CaNa2EDTA, disodium EDTA, disodium ethylenediaminetetraacetate, edetate, edetate calcium disodium, edetic acid, EDTA, Endrate, ethylene diamine tetraacetic acid (EDTA) therapy, ethylenediaminetetraacetic acid.
Note: The term "chelation" refers to the use of any chemical in the blood to remove toxins. This bottom line focuses on EDTA, the most commonly used substance.
Note: EDTA is also known as calcium versenate, disodium ethylenediaminetetraacetate, calcium disodium versenate, CaNa (2) EDTA, CaNa2EDTA, CaEDTA, CaNa2 ethylenediamine tetraacetic acid, ethylenediaminetetraacetic acid, edetate calcium disodium, and calcium ethylenediaminetetraacetate.
Not included in this review: Other substances believed to be useful in chelation include BAL (British Anti-Lewisite or dimercaprol), deferoxamine, dexrazoxane, DMPS (2,3-dimercapto-1-propanesulfonic acid), DMSA (meso-2,3-dimercaptosuccinic or succimer), 2,3-dimercaptosuccinic acid, penicillamine (b,b-dimethylcysteine), deferoxamine (Desferol, used to treat iron overload from multiple transfusions), and some herbal substances.