The spleen is an organ that removes worn-out red blood cells and platelets, produces certain types of white blood cells, and destroys bacteria and cellular debris. Spleen extract primarily comes from the spleens of cows or pigs.
The primary use of spleen extract is after surgical removal of the spleen. Some studies show that spleen extract may stimulate the immune system. However, high-quality studies are lacking.
Some concern has been raised about the safety of spleen extract, as it is made of animal spleens, and it is generally advised to avoid spleen extract from countries where bovine spongiform encephalitis (BSE or "mad cow disease") has been reported.
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These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.