Sangre de grado (the Peruvian name) or sangre de drago (the Ecuadorian name), meaning "blood of the dragon," is a medium-sized tree that grows in the upper Amazon region of Peru, Ecuador, and Colombia. It has large, heart-shaped green leaves and greenish-white flowers. Upon injury to the bark of the tree, a dark red resin spills out of the tree. Sangre de grado is still used in South America as traditional medicine for hemorrhaging and wounds, and as an antiseptic. It is also used for protection against ulcers, including those of the stomach, mouth, throat, and intestines; as an antiviral, anticancer, and antidiarrheal agent; and topically for skin conditions and insect bites.
Compounds isolated from the sap of sangre de grado have been studied for their effects on diarrhea and herpes virus infections. More studies are needed.
2-[4-(3-Hydroxypropyl)-2-methoxyphenoxy]-propane-1,3-diol, 4,5-dihydroblumenol A, alkaloids, alpha-calacorene, alpha-copaene, alpha-pinene, alpha-thujene, beta-caryophyllene, beta-elemene, betaine, beta-pinene, beta-sitostenine, beta-sitosterol, bincatriol, blumenol B, blumenol C, borneol, calamenene, Calamus rotang L., camphene, (+)-catechin, catechins, cedrucine, crofelemer, crolechinic acid, crolechinol, Croton draco Schltdl. & Cham., Croton draconoides Müll. Arg., Croton drago, Croton lechleri Müll. Arg., Croton palanostigma, Croton salutaris, Croton urucurana Baill., Croton xalapensis Kunth, cuparophenol, Daemonorops draco Bl., Daemonorops draco Blume, Daemonorops didymophylla Becc., Daemonorops micranthus Becc., Daemonorops motleyi Becc., Daemonorops propinquus Becc., Daemonorops rubra (Reinw. ex Blume) Mart., daucosterol, dihydrobenzofuran, dimethylcedrusine, dipentene, D-limonene, Dracaena cinnabari Balf.f., Dracaena cochinchinensis Hort. ex Baker, Dracaena draco (L.) L., Draconis palm, drago, (-)-epicatechin, erythro-guaiacyl-glyceryl-beta-O-4'-dihydroconiferyl ether, eugenol, euparophenol, floribundic acid glucoside, gallocatechin, (+)-gallocatechin, (-)-galloepicatechin, gamma-terpinene, gamma-terpineol, glaucine, hardwickiic acid, isoboldine, korberin A, korberin B, lignin, linalool, magnoflorine, methylthymol, myrcene, norisoboldine, Normal Stool Formula, p-cymene, proanthocyanidins, procyanidins, Provir, Pterocarpus officinalis Jacq., resin, sangre de drago, sangue de agua, sinoacutine, SP-300, SP-303, tannin, taspine, terpinen-4-ol, thaliporphine, vanillin.
Note: This monograph will primarily cover Croton lecheri (dragon's blood, dragon's-blood croton, sangre de grado), but not Daemonorops draco (dragon's-blood, dragon's-blood palm).
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Sangre de grado has been studied as a treatment for diarrhea, travelers' diarrhea and diarrhea in AIDS patients, with positive results. However, additional research is needed before a firm conclusion can be made.
Sangre de grado has been studied as a treatment for herpes virus infection in patients with AIDS with positive results. Additional studies are needed before a conclusion can be made.