Royal jelly

background

Royal jelly is a substance that is made in the glands of young nurse worker bees (Apis mellifera). It is used to feed their queen bee and expand her life span over that of other bees. Royal jelly is a milky white liquid that contains many nutrients, including protein, vitamins, and minerals.
Royal jelly is often used to improve general health. It has also been used to treat stomach and hormonal problems, as well as to reduce symptoms of aging and improve mood. Royal jelly has been used to decrease inflammation, blood pressure, and cholesterol levels. It can sometimes be found in cosmetic products for skin problems.
There is a lack of evidence supporting the use of royal jelly for any medical condition.
Royal jelly should be avoided in people who have asthma or any existing allergies, due to the high risk of an allergic reaction.

Related Terms

10-Hydroxy-2-decenoic acid, amino acids, apilak, apisin, B vitamins, bee royal jelly, bee saliva, bee spit, bidro, biotin, carbohydrates, dipeptide YY, DNA, enzymes, flavonoids, gelée royale (French), gelatin, glycoprotein, honey bee milk, honey bee's milk, honeybee royal jelly, honeybee royal jelly-derived collagen production-promoting factor, honeybees (Apis mellifera), hormones, inositol, jalea real (Spanish), jelleines, lait des abeilles (French), lipids, lyophilized royal mletsitse, major royal jelly protein 3, MEL 174 (final water extract of RJ), MEL 247 (dry powder of RJ), minerals, natural royal jelly. neopterin, organic acid glycosides (monoglucosides of 10-hydroxy-2E-decenoic and 10-hydroxydecanoic acids), peptides, protein, RNA, royal bee jelly, royalisin, sterols (including (24Z)-stigmasta-5,24(28)-dien-3beta-ol-7-one, (24Z)-stigmasta-5,24(28)-diene-3beta,7beta-diol, (24Z)-stigmasta-5,24(28)-diene-3beta,7alpha-diol, and (24Z)-stigmast-24(28)-ene-3beta,5alpha,6beta-triol), vitamin A, vitamin C, vitamin D, vitamin E.
Combination products: Pedyphar® (natural royal jelly and panthenol in an ointment base), Melbrosia® (pollen, perga [fermented pollen], hydroxypropylmethyl cellulose, lyophilized royal mletsitse [royal jelly], acerola extract), Lady 4 (evening primrose oil, damiana, ginseng, royal jelly).

evidence table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
 
Diabetic foot ulcers (Grade: C)
Some evidence suggests that an ointment containing royal jelly may help heal diabetic foot ulcers. More research on the effects of royal jelly alone is needed.
Exercise performance (Grade: C)
Although it has not been well studied in humans, animal research suggests that the use of royal jelly combined with other agents may help improve exercise performance. More research is needed.
High cholesterol (Grade: C)
Early research suggests that royal jelly may reduce cholesterol levels. However, available studies are of poor quality, and the findings are still unclear. More well-designed research is needed before firm conclusions can be made.
Male infertility (Grade: C)
Some evidence suggests that applying Egyptian bee honey and royal jelly to the vagina may improve pregnancy rates in women undergoing artificial insemination due to their partners' infertility. Further research is needed on the effects of royal jelly alone.
Menopause (Grade: C)
Early research suggests that herbal products containing royal jelly may improve menopause symptoms. Menopausal women who used Melbrosia® reported reduced discomfort. More research is needed on the effect of royal jelly alone.
Hay fever (Grade: D)
Research suggests that Bidro, a royal jelly product, may lack effect on hay fever prevention or treatment in children. Severe allergic reaction to royal jelly has been shown in numerous reports. More study on the safety of royal jelly is needed.