Pomegranate (Punica granatum)


Pomegranate (Punica granatum) is grown around the world and has a long history of use as food and medicine. In the United States, pomegranate juice and seeds are used as food.
One pomegranate delivers about 40% of an adult's daily vitamin C requirement and is high in antioxidants, which are thought to help reduce the risk of certain diseases. More research is needed before a conclusion can be made on the use of pomegranate for any condition in humans.

Related Terms

Aldehydes, anthocyanins, apigenin, ascorbic acid, ash, beta-sitosterol, beta-sitosterol esters, calcium, catechins, cellulose, citric acid, coemestrol, compound 25, copper, coumestrol, cyanidins, cycloartenol, daucosterol, delphinidins, ellagic acid, ellagitannins, estrone, fatty acids, flavonols, gallic acid, gallotannins, Granada, granatin B, Grenade, Grenadier, humarain, hydroalcoholic extract (HAE), iron, isopelletierine, isoquerecitrin, leucoanthocyanins, luteolin, magnesium, mannitol, methylgallate, minerals, monoterpenes, oleanolic acid, pectin, pelargonidins, pelletierine, phenolic acids, phosphorus, PJ, policosanol, polyphenols, pomegranate extracts, pomegranin, POMx™, potassium, pulicalagin, Punica granatum, Punica proto-punica, Punicaceae, punicalagins, punicalin, punicanolic acid, punicic acid, qualene, quinic acid, Shi liu gen (Chinese), Shi liu gen pi (Chinese), Shi liu pi (Chinese), sodium, sugar alcohols, sugars, tannins, tartaric acid, tocopherols, ursolic acid, vitamin B, vitamin C, zinc.
Combination product examples: Lakewood Organic Pure Pomegranate® (pomegranate juice), Odwalla Pomagrand® (pomegranate juice), POM Wonderful® (pomegranate juice), Pomeratrol™, Radical Fruit® (combination fruit supplement containing pomegranate juice), Swanson Ultra® (pomegranate juice), Weleda® Pomegranate Regenerating Body Care, emerginC® Pomegranate Gel Cleanser, Klorane® No Rinse Care With Pomegranate (conditioner), Radical Fruits®, Xanthigen® (brown marine algae fucoxanthin and pomegranate seed oil (PSO)).

evidence table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Exercise recovery (Grade: B)
Preliminary research suggests that pomegranate may help promote skeletal muscle recovery after exercise and reduce muscle soreness. More studies are needed to confirm these findings.
Aging (Grade: C)
Pomegranate extract has been studied for its antiaging effects on the skin. However, available evidence is weak, and conclusive results cannot be established. Further research is required.
Antifungal (Grade: C)
An extract of pomegranate was shown to be as effective as a commonly used gel when applied to the skin for yeast infection associated with mouth sores. Further research is needed to confirm these effects.
Antioxidant (Grade: C)
Some studies suggest that pomegranate juice may have antioxidant properties, but effects in humans are still unclear. More studies in people with diabetes and cancer are needed.
Atherosclerosis (Grade: C)
Preliminary results of studies using pomegranate for atherosclerosis (hardening of the arteries) are mixed. Pomegranate juice may lower blood pressure in elderly people with high blood pressure. However, further research is needed to confirm these findings.
Chronic obstructive lung disease (Grade: C)
It is unclear whether pomegranate juice is helpful for chronic obstructive lung disease. In theory, pomegranate may be beneficial because of its antioxidant effects, but studies in humans do not support this theory. Additional studies in this area are warranted.
Coronary heart disease (prevention) (Grade: C)
Limited evidence suggests that pomegranate juice may slow progression of coronary heart disease in at-risk people. More studies are needed in this field before any conclusions can be drawn.
Dental conditions (Grade: C)
Extracts from pomegranate fruits may be beneficial in treating dental plaque accumulation and gum disease. More studies are needed.
Erectile dysfunction (Grade: C)
Pomegranate juice has been studied in the treatment of mild-to-moderate erectile dysfunction. Early research is unclear, and more studies are needed before a conclusion can be made.
High blood pressure (Grade: C)
Pomegranate juice may lower blood pressure in patients with high blood pressure.
High cholesterol (Grade: C)
Consumption of a juice containing a combination of fruits, including pomegranate, was found to have a beneficial effect on blood cholesterol levels. Additional studies in which pomegranate alone is used are needed.
Menopausal symptoms (Grade: C)
There is currently not enough evidence to support the use of pomegranate in the reduction of menopausal symptoms.
Metabolic syndrome (Grade: C)
Low-quality studies suggest that pomegranate juice may benefit children who have metabolic syndrome. More research is needed before conclusions can be made.
Prostate cancer (Grade: C)
Consumption of pomegranate juice may benefit people with prostate cancer. Although early research results are promising, more research is needed before conclusions can be made.
Sunburn (Grade: C)
Taking pomegranate extract by mouth may reduce damage to the skin caused by exposure to UV rays. More studies in this area are needed.
Weight loss (Grade: C)
Limited evidence suggests that a combination product containing pomegranate may promote weight loss in obese postmenopausal women. Additional research is needed before any conclusions can be drawn.