Noni (Morinda citrifolia)

background

Noni is a plant that has been used in folk medicine for over 2,000 years in Polynesia. The Polynesians used noni as food, as well as for its antibacterial, antiviral, antifungal, antitumor, anti-parasitic, pain-relieving, blood pressure-lowering, anti-inflammatory, and immune effects.
Noni is a popular supplement. Many studies have reviewd the use of noni; however, strong human evidence is lacking. One trial suggests that noni may benefit people with nausea after surgery. Early research suggests that noni may have antioxidant, cholesterol-lowering, and anticancer activity. Although promising, more high-quality studies are needed.
Cases of liver damage in humans have been reported following noni juice consumption. However, the European Food Safey Authority (EFSA) states that strong evidence is lacking to support an association between noni juice consumption at dietary intake levels and liver problems. More research on the safety of noni is needed.

Related Terms

(-)-3,3'-bisdemethylpinoresinol, (+)-3,3'-bisdemethyltanegool, (+)-3,4,3',4'-tetrahydroxy-9,7'alpha-epoxylignano-7 alpha,9'-lactone, 1,5,15-tri-O-methylmorindol, 2-methoxy-1,3,6-trihydroxyanthraquinone, 2-O-(beta-D-glucopyranosyl)-1-O-hexanoyl-beta-D-gluropyranose, , 2-O-(beta-D-glucopyranosyl)-1-O-octanoyl-beta-D-gluropyranose, 5,15-dimethylmorindol, 5,15-O-dimethylmorindol, 6alpha-hydroxyadoxoside, 6beta,7beta-epoxy-8-epi-splendoside, 9-epi-6a-methoxy geniposidic acid, Al, alizarin, alkaloids, americanin A, amino acids, anthraquinone, anthraquinone glycoside, asperuloside, asperulosidic acid, atchy (Hindi), ß-sitosterol, beta-sitosterol 3-O-beta-d-glucopyranoside, borreriagenin, cada pilva (Malay), caproic acid, caprylic acid, carotene, catechin, citrifolinin A-1, citrifolinin B epimer a, citrifolinin B epimer b, citrifolinoside, citrifolinoside A, cytidine, deacetylasperuloside, deacetylasperulosidic acid, deacetylasp erulosidic acid, dehydromethoxygaertneroside, d-glucose, dilo'k (Pijin), d-mannitol, epicatechin, epi-dihydrocornin, eugenol, flavone glycosides, Indian mulberry, iridoid glycoside, isoscopoletin, kaempferol, kaempferol-3-O-α-L-rhamnopyranoysyl-(1-6)-ß-D-glucopyranoside, kura (Fijian), kuti, ladda (Chamorro), L-asperuloside, linoleic acid, lucidin, maddichettoo (Telugu), manganese, manja-pavattay, Mengkudu, methyl alpha-d-fructofuranoside, methyl beta-d-fructofuranoside, molagha, Morinda citrifolia, Morinda citrifolia fruit juice concentrate, Morinda citrifolia L., Morinda citrifolia Linn, morindacin, morindone, murier d'Inde, najalanun, nakura, narcissoside, nen (Chamorro), niacin, nicotifloroside, nolom, noni berry, noni juice, nonijuice, nono (Cook Islands Maori), nonu (Tongan, Wallisian, Futunian, Niuean, Tokelauan, Tuvaluan), nonu togi (Samoan), noona (Tamil), nordamnacanthal, nowoi (Bislama), octanoic acid, Okinawa noni juice (ONJ), pinoresinol, potassium, proxeronine, quercetin, riro (Tok Pisin), Rubiaceae (family), rubiadin, rubiadin-1-methyl ether, rutin, saponin, scandoside methyl ester, scopoletin, selenium, Tahitian Noni™ Equine Essentials™, Tahitian Noni® Leaf Tea, te non (Gilbertese), terpenoids, uercetin, ursolic acid, vanillin, vitamin A, vitamin C, yelotri.
Select combination products: Tahitian Noni® juice (Morinda citrifolia fruit juice from fruit puree, grape juice concentrate, blueberry juice concentrate, natural flavors), Thrive Adaptogenics, Thrive Adaptogenics Extra, Thrive Adaptogenics Family, Thrive Adaptogenics Max, Thrive Adaptogenics Original (Morinda citrifolia fruit juice from fruit puree, grape juice concentrate, blueberry juice concentrate, natural flavors), Thrive Adaptogenics Pure.

evidence table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
 
Nausea (after surgery) (Grade: B)
One trial shows that noni extract may reduce nausea after surgery. Higher doses (600 milligrams) may be most effective. More research is needed to confirm these early findings.
Antioxidant (Grade: C)
Studies suggest that Tahitian Noni® Juice, which contains noni fruit puree, grape juice, and blueberry juice, may have stronger antioxidant activity than some commonly used antioxidants. In healthy people, Tahitian Noni® Juice may decrease markers of oxidative stress. Tahitian Noni® Juice may also have significant antioxidant benefits in smokers. Further high-quality research is needed on the effects of noni alone.
Cancer (Grade: C)
Noni has been studied for possible benefit in people with cancer. Early research suggests that noni may improve physical function, pain, and fatigue. Noni may decrease the amount of structures in the body that lead to cancer. However, further high-quality research is needed before firm conclusions can be made.
Cervical spondylosis (abnormal wear on neck bones/cartilage) (Grade: C)
Early research suggests that noni juice, combined with physical therapy, may improve neck pain and flexibility in people with cervical spondylosis. Although promising, further high-quality study is needed in this area.
Exercise performance (Grade: C)
Noni juice may enhance exercise performance in athletes. Although promising, more high-quality research is needed on the potential effects of noni alone.
Gum disease (Grade: C)
Early research suggests that Tahitian Noni® Juice may reduce bleeding and inflammation in people with gum disease. However, it lacks an effect on bacteria levels in the mouth. Further high quality research is needed in this area.
Hearing loss (Grade: C)
Noni juice has been used for many years for various conditions in Southeast Asia. Limited research has reviewed the use of noni juice for hearing improvement. Although some benefit was found, further study is needed before conclusions can be made.
High blood pressure (Grade: C)
Limited human research shows that Tahitian Noni® Juice may reduce blood pressure. Lab research suggests that noni may slow or stop the activity of angiotensin converting enzyme, which increases blood pressure. However, further high-quality research is needed to determine the effects of noni alone.
High cholesterol (Grade: C)
According to traditional folk medicine, noni may lower cholesterol. Early research in smokers suggests that Tahitian Noni® Juice may reduce cholesterol and triglycerides in smokers. Although promising, further study is needed before a firm conclusion can be made.
Immune function (Grade: C)
Tahitian Noni Juice may have antioxidant benefits and may affect immune activity in healthy people. Noni may decrease malondialdehyde (MDA), a marker of oxidative stress, and may enhance immune function. Although promising, further high-quality research in this area is needed.
Osteoarthritis (Grade: C)
Early study suggests that people with hip or knee osteoarthritis may experience better quality of life with noni juice consumption. More high-quality research is needed in this field.
Parasites (Grade: C)
Applying a one percent noni ointment to the skin may help treat