Motherwort

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Motherwort (Leonurus species) is a plant that is native to Asia but grows all around the world. The leaves look like the tail of a lion, giving motherwort the nicknames "lion's tail" and "lion's ear."
Motherwort has a long history of use in Chinese medicine. Motherwort has been used most widely for women's health, including childbirth, afterbirth care, irregular menstrual cycles, and premenstrual anxiety, as well as to treat heart disorders.
Motherwort has been studied for use in a variety of conditions, including prostate disorders, arthritis, kidney disease, and stomach problems. However, there is little information on the effects of motherwort alone, and more high-quality trials are needed before conclusions can be made.

Related Terms

Agripalma, agripaume (French), alkaloids, apigenin glucosides, caffeic acid, caffeic acid 4-rutinoside, calcium oxalate, carotenoids, chanshukang granules, Chinese motherwort, coumarins, diterpenes, epicatechin, ferulic acid, flavones, flavonoids, flavonols, genkwanin, herba Leonuri, hydrosols, hyperoside, i-mu-ts'ao (Chinese), iridoides, iridoids, isoquercetrin, Japanese motherwort, kaempferol glucosides, Lamiaceaee (family), leocardin, leonurine, Leonurus, Leonurus artemisia, Leonurus heterophyllus Sweet, Leonurus japonicus Houtt., Leonurus L., Leonurus sibiricus L., lion's ear, lion's tail, LjAMP1, LjAMP2, monosaccharides, monoterpenes, mother wort, mother's wort, polyphenolcarboxylic acids, polyphenols, polysaccharides, procyanidin B2, quercetin, quercetrin, quercitin, quinqueloside, Roman motherwort, rutin, sesquiterpenes, stachydrine, sterols, tannins, throw-wort, triterpenes, vitamin A, volatile oils, wormwood-like motherwort herb, yi mu cao.

evidence table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
 
Anxiety (Grade: C)
Preliminary research compared the effects of motherwort and melatonin to treat anxiety in young adults. Further research is required in this field.
Asthma (Grade: C)
A mixture containing motherwort may benefit children with asthma, compared to other treatments. More research is needed in this area.
Cardiomyopathy (Grade: C)
A mixture containing motherwort used in combination with other medicine has been given to patients with cardiomyopathy (heart muscle disease). More research is needed in this area.
Diabetic complications (Grade: C)
An herbal mixture containing motherwort has been given to people with type 2 diabetes. However, results are unclear, and more research is needed.
Edema (Grade: C)
A mixture containing motherwort has been used to treat women with edema, or swelling due to fluid buildup. There was some evidence of benefit, but more research is needed before conclusions can be made.
Enlarged prostate (Grade: C)
In preliminary research, men with enlarged prostates experienced improvement. Further research is needed before conclusions can be made.
Female infertility (Grade: C)
Use of the motherwort-containing herbal formulation Bushenhuoxuezhuyuntang was associated with increased endometrial thickness compared with control therapy in infertile women. Additional research is needed in this area.
Gout (Grade: C)
A combination product containing motherwort has been studied for treating gout. The results showed that it may be effective, but more research is needed before conclusions can be made.
Heart failure (Grade: C)
A traditional Chinese medicine containing motherwort has been shown to benefit people with chronic heart failure. More research is needed in this area.
Hemorrhage (bleeding) (Grade: C)
Preliminary research found that motherwort treatment given to mothers after a Cesarean section resulted in lower blood loss during surgery, but more blood loss after giving birth, compared to other treatments. Another study looked at the use of a mixture containing motherwort in hemorrhage caused by diabetes. Motherwort has also been studied as part of a treatment plan for bleeding after drug-induced abortion. More high-quality trials are needed.
Irritable bowel syndrome (Grade: C)
A mixture containing motherwort has been used with other medicine to treat stomach disorders such as irritable bowel syndrome, with evidence of benefit. Further studies are needed in this area.
Kidney disease (Grade: C)
Herbal mixtures containing motherwort have been shown to benefit people with kidney disease. More high-quality studies are needed before conclusions can be made.
Liver conditions (Grade: C)
A study compared the effectiveness of combining traditional Chinese and Western medicine to treat to treat liver scarring. The mixture contained motherwort and showed some evidence of benefit, but more research is needed.
Lupus (Grade: C)
A motherwort-containing mixture was used to treat systemic lupus erythematosus, an autoimmune disease. There was evidence of improvement compared to standard therapy. More studies are needed in this area.
Menopausal symptoms (Grade: C)
Preliminary research looked at the effectiveness of a motherwort combination therapy for symptoms of menopause. However, no evidence of benefit was found, and more research is needed before conclusions can be made.
Menstrual disorders (Grade: C)
A motherwort-containing mixture has been used to treat menstrual disorders, with some evidence of benefit. More research is needed.
Painful menstruation (Grade: C)
An herbal mixture containing motherwort has been used to treat painful menstrual periods. Further research is needed in this area.
Pelvic inflammatory disease (Grade: C)
Preliminary research looked at combining Western and traditional Chinese medicine for the treatment of pelvic inflammatory disease. A motherwort-containing herbal mixture showed some evidence of benefit. More studies are needed in this area.
Polycystic ovarian syndrome (hormone imbalance) (Grade: C)
One study looked at the effect of a motherwort-containing herbal treatment on polycystic ovarian syndrome. Compared to the control therapy, it resulted in significant improvement. Further research is needed in this area.
Sedative (Grade: C)
A combination herbal product containing motherwort was studied for its effect on symptoms linked to abstaining from alcohol in alcohol-dependent men, and it showed evidence of benefit. Further research is needed.