Nutmeg and mace are two commonly used spices originating from the same tree, Myristica fragrans. Nutmeg is derived from the seed of the tree and mace from the seed covering.
Nutmeg has a history of abuse as a popular recreational psychoactive drug. However, mace does not have a history of this use.
Based on human study, mace extract, when used as part of a chewing gum, may decrease plaque and gingivitis. Although not well studied in humans, mace extract may also have antibacterial, antifungal, anti-inflammatory, and anticancer effects. Mace is a popular medicine in India to treat measles.

Related Terms

Aflatoxins, alpha-pinene, alpha-terpineol, basbas (Arabic), basbasah (Arabic), basbaz (Persian), beta-phellandrene, beta-pinene, bicuiba (Portuguese), borneol, buah pala (Malay), bunga pala (Malay), chan thet (Thai), chant heed (Laotian), cineole, dâu khâu (Vietnamese), diarylpropanoids, dihydroguaiaretic acid (DHGA), dilignan, dok chand (Thai), elemicin, estragole, eugenol, fleur de muscade (French), flor de noz moscada (Brazilian Portuguese), foelie (Dutch), gamma-terpinene, gerinol, industan djevisi (Turkish), isoeugenol, jaaiipatrii (Nepali), jaayphala (Hindi), jadikkai (Tamil), jaephal (Hindi), jaiphal (Bengali), jaiphul (Hindi), jaitri (Hindi), jajikaia (Telugu), jajipatri (Sanskrit), jajiphalam (Sanskrit), japatri (Telugu), jathi seed (Malayalam), jathikkai (Thai), jati pattiri (Tamil), jatikka (Tamil), javitri (Hindi), jayaphal (Nepali), josat al teeb (Arabic), jousbuva (Arabic), jouzboyah (Persian), jouzuttib (Arabic), kambang pala (Malay, Java), kembang pala (Malay), licarin-B, lignans (macelignan), ligroin, look jun (Thai), macia (Spanish), macis (French, Spanish), malabaricone B, malabaricone C, meso-dihydroguaiaretic acid (DGA), methoxyeugenol, methyleugenol, moscada (Spanish), moscadeira (Portuguese), moscadero (Spanish), moschokarydo (Greek), muscadier (French), Muskatbaum (German), Muskatblüte (German), muskatnii orekh (Russian), muskatnød (Danish), muskatnogo orekha (Russian), muskatnoi drechi (Russian), Muskatnuβ (German), Muskatnuβbaum (German), muskott (Swedish), myristic acid, myristica, Myristica argentea, Myristica cagayanensis, Myristica fragrans, Myristica malabarica, Myristica officinalis, Myristicaceae (family), Myristicae aril, Myristicae semen, myristicin, neolignans, nhuc dâu khau (Vietnamese), nikuzuku (Japanese), noce moscata (Italian), nogal moscado (Spanish), noix de banda (French), noix muscade (French), nootmuskaat (Dutch), nootmuskaatboom (Dutch), noz moscada (Brazilian Portuguese), nuez moscada (Spanish), nutmeg, nux moschata, nuz moscada (Portuguese), otobaphenol, pala (Indonesian), pala banda (Malay), pattiri (Tamil), pied de muscade (French), resorcinols, rou dou kou (Chinese), rou dou kou yi (Chinese), rou guo (Chinese), rou kou (Chinese), sadikka (Sinhalese), safrole, sekar pala (Malay), sushonaya shelukha (Russian), taiphal (Hindi), taipmal (Hindi), taukau (Chinese), terpene, terpinen-4-ol, terpineol, trimyristin, vicuiba (Telugu), volatile oil, yu guo (Chinese), yu guo hua (Chinese), zadeikpo (Burmese).
Note: This monograph focuses on mace, not nutmeg; mace is the aril (seed covering) of the nutmeg seed (Myristica fragrans).

evidence table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Gingivitis (Grade: C)
In human study, chewing gum containing mace extract resulted in reduced plaque and gingival inflammation. Additional study is needed in this area.