Gymnema (Gymnema sylvestre R. Br.)
Preliminary human evidence suggests that gymnema may be effective in the management of blood sugar levels in type 1 and type 2 diabetes, as an adjunct to conventional drug therapy, for up to 20 months. Gymnema appears to lower serum glucose and glycosylated hemoglobin (HbA1c) levels following chronic use, but may not have significant acute effects. High-quality human trials are lacking in this area. Some of the available research has been conducted by authors affiliated with manufacturers of gymnema products.
Asclepiadaceae (family), Asclepias geminata roxb., Gemnema melicida, GS4 (water soluble extract of the leaves), gur-mar, gurmar, gurmarbooti, Gymnema inodum, Gymnema montanum, Gymnema sylvestre, kogilam, madhunashini, mangala gymnema, merasingi, meshashringi, meshavalli, miracle plant, periploca of the woods, Periploca sylvestris, podapatri, Proβeta®, ram's horn, small Indian ipecac, sarkaraikolli, shardunika, sirukurinja, vishani.
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Preliminary human research reports that gymnema may be beneficial in patients with type 1 or type 2 diabetes when it is added to diabetes drugs being taken by mouth or to insulin. Further studies of dosing, safety, and effectiveness are needed before a strong recommendation can be made.
Preliminary research in people with type 2 diabetes reports decreased cholesterol and triglyceride levels. Better evidence is needed before a clear conclusion can be made.
extract (GSE) has been shown to be effective for weight loss when used in combination with other products. The effects of gymnema are difficult to determine, and additional high-quality trials using gymnema alone are needed to confirm these results.