Green-lipped mussel


The green-lipped mussel is native to the New Zealand coast and is a staple in the diet of the indigenous Maori culture. The anti-inflammatory effects of green-lipped mussel have been studied since the observation of a lower incidence of arthritis in coastal Maoris compared with European or inland Maori people.
Products containing green-lipped mussel are used to treat inflammatory conditions such as asthma, osteoarthritis, and rheumatoid arthritis. Evidence of an effect in asthma and osteoarthritis is unclear, while evidence suggests green-lipped mussel is not effective in treating rheumatoid arthritis.

Related Terms

Betain, brevetoxin B analog B4, BTXB4, chondroitin sulfate, eicosatetraenoic acids, freeze-dried mussel powder, glycosaminoglycans, green lipped mussel, Green Lips®, green shell mussel, Greenback®, Greenshell®, Greenshell® Mussel, heparin, Lyprinol®, marine oils, mollusk, Mytilidae (family), New Zealand green-lipped mussel, okadaic acid, pectenotoxins, Perna canaliculus, pernin, shellfish lipid extract, Seatone, sterol esters, yessotoxins.

evidence table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Asthma (Grade: C)
Limited evidence suggests that green-lipped mussel supplementation may help allergic diseases, such as atopic asthma. Additional research is needed before a recommendation can be made.
Osteoarthritis (Grade: C)
There is conflicting evidence of the effect of green-lipped mussel supplementation for treating osteoarthritis. Reliable evidence is needed to determine whether green-lipped mussel is effective for this use.
Rheumatoid arthritis (Grade: D)
There is conflicting evidence of the effect of green-lipped mussel supplementation for treating rheumatoid arthritis. Overall, the evidence does not support this use.