Greater celandine


Greater celandine has been used historically in Europe for the treatment of many diseases. Although celandine is considered somewhat toxic, it has been used in traditional Chinese medicine and by German doctors.
A semisynthetic drug that uses greater celandine extracts, called UkrainTM, has been studied for the treatment of cancer and may gain more attention in the future because of its antiosteoporosis effects.

Related Terms

Berberine, C. majus, chelerythrine, chelidonine, Chelidonium majus, Chelidonium-30 (Ch-30), Chelidonium-200 (Ch-200), coptisine, greater celandine grass, Iberogast®, NSC 61570, Papaveraceae (family), Schollkraut (German), STW 5 (Iberogast®), stylopine, Ukrain™, UKSR-222.

evidence table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Cancer (general) (Grade: B)
Ukrain™, a semisynthetic drug derived from
Biliary colic (Grade: C)
Esophageal cancer (Grade: C)
The majority of studies on the use of
Lung cancer (Grade: C)
The effects of Ukrain™ in lung cancer patients are comparable to its effects in other types of cancer. It appears to improve immune system function in cancer patients who concurrently demonstrate clinical improvement. Limited research suggests that further research in this area is warranted.
Pancreatic cancer (Grade: C)
Ukrain™ has demonstrated some benefit, such as increased survival time, even in the most advanced, untreatable forms of cancer. Patients with "untreatable" cancers are a suitable population for research into complementary cancer treatments, as they are not being deprived of other known therapies when participating in such studies. Further research is needed.
Tonsillitis (Grade: C)
Traditionally, herbalists and naturopathic doctors have used herbs in the form of tinctures, or alcohol extracts.