Andrographis , Kan Jang®, SHA-10

background

The leaves of Andrographis paniculata have been as part of Indian folk medicine and Ayurveda for centuries. The Chinese and Thai herbal medicine systems have also used this herb, mostly for its "bitter" properties, as a treatment for digestive problems and for a variety of fever-causing illnesses. More recently, this herb has become popular in Scandinavia as a remedy for upper respiratory infections (URIs) and the flu.
The most widely tested product is a product called Kan Jang® (Swedish Herbal Institute). This product is available with andrographis alone and in combination with Eleutherococcus senticosus.
There is reasonably strong evidence from clinical trials to suggest that andrographis effectively reduces the severity and the duration of URIs. Based on animal and laboratory studies, andrographis may have a number of other potential therapeutic uses, including as an anti-inflammatory agent and as a treatment for chemically-induced liver damage. It has also been studied in human clinical trials for the flu and familial Mediterranean fever.

Related Terms

Andrographolide, Chuan Xin Lin, Green chiretta, Kalmegh leaf extract, Kan Jang®, King of Bitters, Kold Kare®, Remdex®.

evidence table

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
 
Upper respiratory tract infection: treatment (Grade: A)
Research suggests that andrographis may reduce symptom severity and duration in active infections if started within 36-48 hours after symptoms develop. Additional studies are needed, especially those that test the effects of andrographis alone.
Familial Mediterranean fever (Grade: C)
Familial Mediterranean fever is a genetic disorder that mainly affects ethnic groups around the Mediterranean causing recurrent episodes of fever and swelling of serous membranes. While early studies suggest that a combination product containing andrographis may reduce the duration, frequency, and severity of attacks among children, more studies using andrographis alone are needed.
Influenza (flu) (Grade: C)
Early studies suggest that andrographis may reduce the duration and severity of flu symptoms, as well as the amount of sick time taken off from work by patients with the flu. More research is needed to confirm these results.
Upper respiratory tract infection: prevention (Grade: C)
Early studies suggest that andrographis extract may help prevent URIs during the winter months if taken daily. Larger studies are required to confirm these results.