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Charles Drake

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Charles Drake
CUIMC/Herbert Irving Pavilion Office

(212) 305-5098

 161 Fort Washington Avenue New York, NY 10032
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About

Charles Drake

Dr. Charles G. Drake is a physician-scientist with a Ph.D. in immunology, whose work focuses on understanding and fighting advanced-stage cancers with the immune system. He is known for rapidly incorporating discoveries made in the research lab into innovative clinical trials, including anti-tumor vaccines. The Drake laboratory was the first group to show that LymphocyteActivation Gene–3 (LAG-3) is a cell surface marker for CD4 cells with regulatory function (Treg) and that blockade of LAG-3 with a monoclonal antibody could restore anti-tumor immune responses by mitigating CD8 T-cell tolerance in vivo. Further work demonstrated that LAG-3 and PD-1 were co-expressed on functionally exhausted CD8 T cells, suggesting that blockade of multiple immune checkpoints might be required to restore anti-tumor immunity. These discoveries were then translated into clinical trials. His most recent work has focused on the body’s immunological response to radiation therapy and how immunotherapy and radiation therapy can be used in concert to treat cancer. His research has been published in prestigious journals such as the New England Journal of Medicine, Cancer Research, the Journal of Clinical Investigation, and the Journal of Clinical Oncology. Prior to joining NewYork-Presbyterian/Columbia, Dr. Drake served as the co-director of the Cancer Immunology Program at Johns Hopkins Kimmel Cancer Center. He is also a professor of oncology, urology, and immunology. As co-director of the Prostate Cancer Multi-Disciplinary Clinic, he developed a novel transgenic model of prostate cancer, in which a unique antigen is expressed exclusively in the prostate gland and in prostate tumors. Dr. Drake received both his bachelor’s degree in electrical engineering and his master’s degree in biomedical engineering from Rutgers University. He completed a Ph.D. program at the National Jewish Center for Immunology and Respiratory Medicine at the University of Colorado Health Sciences Center, and later earned his M.D. from the University of Colorado as part of the MSTP program. He did his internship and residency in internal medicine at the Osler Medical Service of Johns Hopkins Hospital, and did his medical oncology fellowship training in the Johns Hopkins Department of Oncology.
Primary Specialty

Oncologist

Practice CUIMC/Herbert Irving Pavilion
Gender Male
Accepting New Patients
Insurances Accepted Emblem/Hip, Multiplan, Empire Blue Cross Blue Shield Healthplus, Local 1199, MVP Health Care, UnitedHealthcare, Affinity Health Plan, Emblem/GHI, Fidelis Care, Medicare, RiverSpring, Quality Health Management, WellCare, AgeWell, Healthfirst, World Trade Center Health Plan, CIGNA, Amida Care, Magnacare (National), AETNA, Empire Blue Cross/Blue Shield, VNSNY CHOICE
Degrees Medical Doctor, Doctor of Philosophy
Office Name CUIMC/Herbert Irving Pavilion
Map and Directions
161 Fort Washington Avenue, New York, NY 10032
Services CUIMC/Herbert Irving Pavilion provides oncology services in New York, NY. Oncology includes the diagnosis and treatment of breast cancer, skin cancer, prostate cancer, and many other forms of cancer.

Contact Charles Drake at (212) 305-5098 for specific information about cancer treatment in New York, NY. Additional Services Hematologist, Doctor
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