Prader-Willi syndrome


Prader-Willi syndrome is a rare genetic disorder that causes decreased muscle tone, mild-to-moderate intellectual disability, and an intense appetite during childhood and adulthood. Behavioral problems, such as a quick temper or obsessive-compulsive disorder, are also common.
Because they often have poor muscle tone at birth, children born with Prader-Willi syndrome may have difficulty feeding until they are about one year old. However, children soon develop insatiable appetites and typically gain weight rapidly. As a result, individuals with this disorder are often overweight or obese. Many of the complications of Prader-Willi syndrome, including diabetes, sleep apnea, high blood pressure, right-sided heart failure, and joint problems, are caused by obesity.
It is estimated that one out of 10,000-25,000 people worldwide have Prader-Willi syndrome.
There is no cure for Prader-Willi syndrome. However, many treatments and therapies may help patients cope with the disorder and help prevent complications. Weight control is especially important to prevent complications of obesity.

Related Terms

Binge eating, chromosome 15, cryptorchidism-dwarfism-subnormal mentality, HHHO, hypogenital dystrophy with diabetic tendency, hypotonia, hypotonia-hypomentia-hypogonadism-obesity syndrome, insulin resistance, Labhart-Willi syndrome, metabolic syndrome, obesity, overweight, Prader-Labhart-Willi Fancone syndrome, PWS, strabismus, translocation, uniparental disomy, Willi-Prader syndrome.