Amyloidosis is a rare and potentially fatal disease that occurs when amyloid proteins build up in the body's tissues and organs. The abnormal protein is produced by cells in the bone marrow.
Amyloidosis affects different organs in different individuals. However, it usually occurs in the heart, kidneys, liver, spleen, nervous system and gastrointestinal tract.
There are several different types of amyloidosis. The disease is classified based on where the protein is produced. The most common type of the disease, primary systemic amyloidosis, is a bone marrow disorder. Other types, which originate in the liver, are considered to be familial or inherited. Amyloidosis may also be the result of kidney disease in people who have undergone long-term dialysis.
The exact cause of amyloidosis is unknown, and currently there is no cure for the disease. However, medications and special diets may help relieve symptoms and reduce the production of the amyloid protein.
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