Stevia Dosing and Safety

safety

Allergies

Avoid in people with a known allergy or sensitivity to stevia or to members of the daisy family (Asteraceae/Compositae). Other members of the daisy family include ragweed, chrysanthemums, marigolds, and many other herbs.

Side Effects and Warnings

Stevia is likely safe when 250-500 milligrams are taken by mouth three times daily for up to two years in Chinese adults with high blood pressure. This dose range is possibly safe in non-Chinese adults with high blood pressure.
Stevia may cause altered kidney function, changes in blood vessel width, changes in sodium excretion, changes in urine flow, decreased body strength, dizziness, muscle pain or weakness, nausea, and stomach fullness.
Stevia may cause low blood pressure. Caution is advised in people taking agents, herbs or supplements that lower blood pressure.
Stevia may lower blood sugar levels. Caution is advised in people with diabetes or low blood sugar, and in those taking agents, herbs, or supplements that affect blood sugar. Blood sugar levels may need to be monitored by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.
Use cautiously in people with kidney disease or dysfunction or those with low blood calcium.
Use cautiously in people who are taking agents that affect blood vessel width, including calcium channel blockers.
Use cautiously in children and in pregnant or breastfeeding women.
Use cautiously if using stevia for longer than two years.
Avoid in people with a known allergy or sensitivity to stevia or to members of the daisy family (Asteraceae/Compositae).

Pregnancy and Breastfeeding

There is a lack of scientific evidence on the use of stevia during pregnancy or breastfeeding.

dosing

For high blood pressure, 250-500 milligram capsules of stevioside or stevioside powder have been taken by mouth three times daily for three months up to two years. Up to 15 milligrams per kilogram of crude steviosides have been taken by mouth twice daily for 24 months.
For high blood sugar, one gram of stevioside has been taken by mouth with a single meal. Five grams of water-based stevia leaf extracts have been taken by mouth every six hours for three days.

Children (under 18 years old)

There is no proven safe or effective dose for stevia in children.

interactions

Interactions with Drugs

Stevia may cause low blood pressure. Caution is advised in people taking agents that lower blood pressure, including vasodilators such as calcium channel blockers.
Stevia may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. People taking insulin or agents for diabetes by mouth should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.
Stevia may also interact with agents that affect blood vessel width, agents that increase urination, agents used for the heart, anticancer agents, antifungals, anti-inflammatories, antimicrobials, antivirals, appetite suppressants, calcium channel blockers, cholesterol-lowering agents, fertility agents, hormonal agents, memory-enhancing agents, and sodium monoketocholate (MKC).

Interactions with Herbs and Dietary Supplements

Stevia may cause low blood pressure. Caution is advised in people taking herbs or supplements that lower blood pressure.
Stevia may lower blood sugar levels. Caution is advised when using herbs or supplements that may also lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.
Stevia may also interact with anticancer herbs and supplements, antifungal herbs and supplements, anti-inflammatory herbs and supplements, antimicrobials, antioxidants, antiviral herbs and supplements, catechin, cholesterol-lowering herbs and supplements, herbs and supplements for appetite suppression, herbs and supplements that affect blood vessel width, herbs and supplements that increase urination, herbs and supplements used for fertility, herbs and supplements used for the heart, hormonal herbs and supplements, and memory-enhancing herbs and supplements.