Chlorophyll

safety

Allergies

Avoid in individuals with a known allergy or hypersensitivity to chlorophyll or any of its metabolites; contact may result in a photosensitive rash. Copper chlorophyll (E141) could be a pseudoallergen.

Side Effects and Warnings

It appears that chlorophyll is generally safe and without many side effects or toxicities in non-sensitive people. Adverse effects are usually gastrointestinal or dermatologic in nature. Common gastrointestinal complaints may include nausea, diarrhea, green stools, and abdominal cramping. When taken by mouth, chlorophyllin may cause green discoloration of the urine.
Use cautiously in patients who show signs of photosensitivity, such as a rash, to chlorophyll or any of its metabolites.
Use cautiously in patients with compromised liver function due to the possibility of the development of jaundice.
Use cautiously in patients taking immunosuppressant agents as chlorophyll may normalize T lymphocyte counts.
Use cautiously in patients with diabetes or taking diabetes agents as chlorophyll may have antidiabetic effects.

Pregnancy and Breastfeeding

Chlorophyll is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence.

dosing

Adults (18 years and older):

There is no proven effective dose for chlorophyll. For bad breath, 100 milligrams has been taken two or three times daily. For colostomy odor, 75 milligrams three times daily for up to 100-200 milligrams daily in divided doses has been used. 300 milligrams daily has been used if odor was still not controlled. 1-2 tablets of 100 milligrams have been placed in the empty pouch each time it is reused or changed in a patient who has had an ostomy. For protection from aflatoxins, chlorophyllin 100 milligrams three times daily for four months has been studied. For pancreatitis, an infusion of 5-20 milligrams water-soluble chlorophyll-a daily for one to two weeks followed by intermittent administration thereafter has been used. For pneumonia, infusion of 0.25% chlorophyllypt solution in physiological sodium chloride solution administered by intravenous drip has been studied.
Theoretical evidence suggests chlorophyll may aid the growth of new tissue when applied topically (on the skin) for burns and wounds.

Children (younger than 18 years):

There is no proven effective dose for chlorophyll in children.

interactions

Interactions with Drugs

The chlorophyll metabolite phytanic acid may have antidiabetic activity. Caution is advised when using medications that may lower blood sugar. Patients taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.
Phytanic and pristanic acids are thought to affect catabolic lipid metabolism. Caution is advised when taking chlorophyll with agents that lower cholesterol, such as statins.
Although not well studied in humans, chlorophyll or its metabolites may have antineoplastic (anticancer) properties. Caution is advised in patients taking other anticancer agents.
The chlorophyll metabolites phytanic and pristanic acids may have antiobesity properties. Caution is advised when taking chlorophyll and other agents for weight loss.
Chlorophyll may have antioxidant and antiviral properties. Caution is advised in patients taking drugs with antioxidant and antiviral properties due to possible additive effects.
Chlorophyll may have detoxifying effects, especially dioxins, polychlorinated dibenzofurans (PCDFs) and polychlorinated dibenzo-p-dioxins (PCDDs).
Chlorophyll and some of its synthetically produced derivatives may be photosensitizing. Chlorophyll may cause hyperpigmentation, dermatitis, or make a patient more sensitive to laser treatment.

Interactions with Herbs and Dietary Supplements

Phytanic and pristanic acids are thought to affect catabolic lipid metabolism. Caution is advised when taking chlorophyll with herbs or supplements that lower cholesterol, such as red yeast rice.
Although not well studied in humans, chlorophyll or its metabolites may have antineoplastic (anticancer) properties. Caution is advised in patients taking anticancer herbs or supplements.
Chlorophyll may have antioxidant and antiviral properties. Caution is advised in patients taking herbs or supplements with antioxidant and antiviral properties due to possible additive effects.
Although not well studied in humans, chlorophyll may have detoxifying effects, especially dioxins, polychlorinated dibenzofurans (PCDFs) and polychlorinated dibenzo-p-dioxins (PCDDs).
The chlorophyll metabolite phytanic acid may have antidiabetic activity. Caution is advised when using herbs or supplements that may lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.
Chlorophyll and some of its synthetically produced derivatives may be photosensitizing. Chlorophyll may cause hyperpigmentation, dermatitis, or make a patient more sensitive to laser treatment. Beta-carotene or canthaxanthin may prevent or lessen chlorophyll-induced photosensitivity.
Although not well studied in humans, vitamin C (ascorbic acid) and pantothenic acid may exert preventative effects against photosensitized hemolysis.
The chlorophyll metabolites phytanic and pristanic acids may have antiobesity properties. Caution is advised when taking chlorophyll and other herbs or supplements for weight loss.