Chlorophyll Dosing and Safety

safety

Allergies

Avoid if allergic or sensitive to chlorophyll or any of its parts. Chlorophyll may cause an allergic reaction to the sun and intolerance to copper chlorophyll in food has been reported.

Side Effects and Warnings

Chlorophyll is likely safe when taken by mouth at recommended doses.
Chlorophyll may affect blood sugar levels. Caution is advised in people with diabetes or low blood sugar, and in those taking drugs, herbs, or supplements that affect blood sugar. Blood sugar levels may need to be monitored by a qualified healthcare professional, including a pharmacist, and medication adjustments may be necessary.
Use cautiously in people who have heart conditions. Chlorophyll may cause chest pain.
Use cautiously in people who have stomach disorders. Chlorophyll may cause changes in stool color, diarrhea, dry mouth, nausea, and stomach cramps.
Use cautiously in people who have liver problems. Chlorophyll may cause pseudojaundice (changes in skin color due to blood changes).
Chlorophyll may interfere with the way the body processes certain drugs, herbs, or supplements using the liver's "cytochrome P450" enzyme system. As a result, the levels of these agents may be altered in the blood, and may cause potentially serious adverse reactions. People using any medications should check the package insert, and speak with a qualified healthcare professional, including a pharmacist, about possible interactions.
Use cautiously in people taking agents that may affect the immune system. Chlorophyll may affect immune cells.
Use cautiously in people who have light sensitivity or rash. Chlorophyll may cause light sensitivity, rash, and skin irritation.
Avoid in children and in pregnant or breastfeeding women, due to a lack of safety data.
Avoid if allergic or sensitive to chlorophyll or any of its parts.
Chlorophyll may also cause changes in urine color, food intolerance (caused by copper chlorophyll), and porphyria (disorder in which heme protein is not made properly).

Pregnancy and Breastfeeding

There is a lack of scientific evidence on the use of chlorophyll during pregnancy or breastfeeding. Avoid in pregnant or breastfeeding women due to a lack of safety data.

dosing

Adults (18 years and older)

To treat bad breath, 100 milligrams of chlorophyll has been taken by mouth two or three times daily.
To treat low white blood cell count, 40 milligrams of sodium copper chlorophyllin (Yebaike™ tablet) has been taken by mouth three times daily for one month.
To protect from aflatoxins, 100 milligrams of chlorophyllin has been taken by mouth three times daily for four months.
To reduce odor caused by urinary problems, 100 milligrams of chlorophyllin (Derifil®) has been taken by mouth daily for two weeks. 100-300 milligrams of chlorophyll has been taken by mouth daily in single or divided doses. One or two tablets of 100 milligrams have been placed in the empty pouch each time it is reused or changed in people who have had an ostomy.
To treat cancer, 0.1 grams per centimeter squared of Radachlorin® gel has been applied to the skin during 1-3 hours of exposure to 400-800 joules per centimeter squared light therapy at interval schedules of two sessions over four weeks, three sessions over one week, or four sessions over one week, for up to 18 months. A dose of 3-6 milligrams per meter squared of HPPH (2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a) has been applied to the skin 24-48 hours before exposure to 150, 175, or 200 joules per centimeter of 665 nanometer light. Sonoflora 1 has been placed under the tongue 24 hours before therapy. A dose of 0.5-1.2 milligrams per kilogram of Radachlorin® has been injected into the vein together with 200-300 joules per centimeter squared of laser treatment at interval schedules of two sessions over four weeks, three sessions over one week, or four sessions over one week, for up to 18 months.
To treat herpes, 2-5 milligrams of chlorophyll per 1 gram of cream or per 1 milliliter of saline solution has been applied to affected areas 3-6 times daily.
To treat sepsis (severe reaction to bacteria), 1 percent Chlorophyllipt® ethanol solution has been applied to the skin.
To treat inflammation of the pancreas, a dose of 5-20 milligrams of water-soluble chlorophyll-a has been injected into the vein daily in 1-2 divided doses for periods of three days to three years, for a total chlorophyll-a intake ranging from 30-1,960 milligrams.

Children (under 18 years old)

There is no proven safe or effective dose for chlorophyll in children.

interactions

Interactions with Drugs

Chlorophyll may affect blood sugar levels. Caution is advised when using medications that may also affect blood sugar. People taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.
Chlorophyll may interfere with the way the body processes certain drugs using the liver's "cytochrome P450" enzyme system. As a result, the levels of these drugs may be increased in the blood, and may cause increased effects or potentially serious adverse reactions. People using any medications should check the package insert, and speak with a qualified healthcare professional, including a pharmacist, about possible interactions.
Chlorophyll may also interact with agents that may affect the blood, agents that may affect the immune system, agents that may increase light sensitivity, agents that may prevent mutation, anticancer agents, antiseptics, antivirals, cholesterol-lowering agents, detoxifying agents, heart agents, skin agents, stomach agents, and weight loss agents.

Interactions with Herbs and Dietary Supplements

Chlorophyll may affect blood sugar levels. Caution is advised when using herbs or supplements that may also affect blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.
Chlorophyll may interfere with the way the body processes certain herbs or supplements using the liver's "cytochrome P450" enzyme system. As a result, the levels of other herbs or supplements may become too high in the blood. It may also alter the effects that other herbs or supplements possibly have on the P450 system.
Chlorophyll may also interact with anticancer herbs and supplements, antioxidants, antivirals, carotenoids, cholesterol-lowering herbs and supplements, detoxifying herbs and supplements, herbs and supplements that may affect the blood, herbs and supplements that may affect the immune system, herbs and supplements that may increase light sensitivity, herbs and supplements that may prevent mutation, herbs and supplements that may protect against radiation, herbs and supplements that may treat heart disorders, herbs and supplements that may treat stomach disorders, pantothenic acid, vitamin C, and weight loss herbs and supplements.