Baikal skullcap (Scutellaria barbata)
safety
Allergies
Avoid in people with a known allergy or hypersensitivity to Baikal skullcap (Scutellaria barbata), its constituents, or members of the Lamiaceae family.
Side Effects and Warnings
Baikal skullcap is an ingredient in PC-SPES, a product that has been recalled from the U.S. market and should not be used.
Adverse effects may include nausea, diarrhea, flatulence, vomiting, constipation, fatigue, and headache.
Use cautiously in patients taking sedatives and/or operating heavy machinery.
Use cautiously in patients taking therapies for cancer, especially cyclophosphamide.
Use cautiously in patients taking therapies broken down by the liver.
Avoid in patients who are pregnant or breastfeeding, due to a lack of scientific evidence.
Pregnancy & Breastfeeding
Baikal skullcap is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence.
dosing
Adults (over 18 years old)
There is no proven safe or effective dose for Baikal skullcap in adults.
Children (under 18 years old)
There is no proven safe or effective dose for Baikal skullcap in children.
interactions
Interactions with Drugs
Scutellaria baicalensis Georgii extract may help treat 5-fluorouracil-induced bone marrow damage.
Caution is advised in patients taking antibiotics, antifungals, antihistamine medications, antiviral agents, and anti-inflammatory medications, due to possible additive effects.
Scutellaria baicalensis radix extract may increase or decrease serum lipid levels. Use cautiously with cholesterol-lowering medications, due to possible additive effects.
Caution is advised in patients with cancer or taking anti-cancer medications, due to possible additive effects.
Baikal skullcap may have antioxidant activity. Caution is advised in patients taking antioxidant agents, due to possible additive effects.
Baikal skullcap may interact with drugs that are broken down by the liver.
Baikal skullcap is used in traditional Chinese medicine (TCM) as a diuretic.
Baikal skullcap may cause drowsiness and have additive effects with other sedatives.
Interactions with Herbs & Dietary Supplements
Use cautiously with herbs and supplements with antibacterial activity, antifungal activity, antihistamine activity, anti-inflammatory activity, antioxidant, and antiviral activity, due to possible additive effects.
Scutellaria baicalensis radix extract may increase or decrease cholesterol levels. Use cautiously with cholesterol-lowering herbs and supplements due to possible additive effects.
Use cautiously in patients with cancer and in those taking herbs or supplements to treat cancer.
Baikal skullcap may reduce the berberine content in berberine-containing herbs.
Baikal skullcap may interact with herbs and supplements that are broken down by the liver.
Baikal skullcap is used in traditional Chinese medicine (TCM) as a diuretic.
Scutellaria baicalensis dry extract and baicalin may interact with hematological (blood) agents.
Baikal skullcap and Oldenlandia diffusa in combination exhibited additive antimutagenic effects.
PC-SPES contains Baikal skullcap, and thus additive effects may occur in theory.
Baikal skullcap may cause additive drowsy effects when take with sedatives. Caution is advised if driving or operating machinery.
