Avoid in individuals with a known allergy or hypersensitivity to acacia or the Fabaceae or Leguminosae family. There is cross-sensitivity between acacia and rye grass pollen allergens and date palm.
Avoid in individuals with a known allergy or hypersensitivity to pollen, particularly mimosa, other pollens, bee pollen, other inhalants and foods containing related substances.
Side Effects and Warnings
Acacia gum is regarded as safe when used orally and in amounts commonly found in foods. Acacia has generally recognized as safe status (GRAS) for use in foods in the United States.
When sucked or chewed, acacia may cause gastrointestinal disturbances and neurological side effects.
Allergic reactions including asthma, rhinitis, conjunctivitis and rash may occur.
Acacia senegal can cause minor gastrointestinal disturbances such as bloating, loose stools, and flatulence. Side effects may diminish with continued use.
Iridocyclitis, a type of anterior uveitis, can be caused by acacia thorns.
Use cautiously in patients taking amoxicillin or iron.
Use cautiously in patients with respiratory disorders
Be aware that the fiber of acacia may impair the absorption of oral drugs.
Be aware that tannins from Acacia catechu L. plant may contribute to oral and esophageal cancer when combined with other substances that also contain high amounts of tannins.
Pregnancy and Breastfeeding
Acacia is not recommended in pregnant or breastfeeding women due to a lack of available scientific evidence.
Adults (18 years and older)
There is no proven safe or effective dose for Acacia. Traditionally, 5 grams twice daily for four weeks has been used.
Daily use of a chewing stick of Acacia arabica may be effective for plaque; studies have shown positive results in as little as seven days.
Children (younger than 18 years)
Insufficient available evidence to recommend.
Interactions with Drugs
Acacia may affect the absorption of amoxicillin when taken concurrently; doses should be separated by at least four hours.
Use of acacia as a surfactant (substance that lowers surface tension) may increase the intestinal absorption of some anticancer drugs.
Mixing acacia with a substance containing more than 50% concentration of ethyl alcohol may cause acacia to become insoluble.
Acacia can be gelatinized by solutions of iron salts.
Theoretically, the fiber in acacia may impair the absorption of oral drugs.
Interactions with Herbs and Dietary Supplements
Theoretically, the fiber in acacia may impair the absorption of oral herbs and supplements.
Theoretically, tannins from Acacia catechu L. plant may contribute to oral and esophageal cancer when combined with other substances that also contain high amounts of tannins.