Sea buckthorn (Hippophae rhamnoides) Dosing and Safety

safety

Allergies

Avoid in people with known allergy or sensitivity to sea buckthorn, its parts, or other members of the Elaeagnaceae family.

Side Effects and Warnings

Sea buckthorn is likely safe when used in amounts normally found in food.
Sea buckthorn is possibly safe when used in amounts for medicinal purposes for fewer than six months.
Sea buckthorn may cause abnormal heart rhythms, changes in heart rate, changes in the immune system, dizziness, headache, rash, tissue swelling (caused by fluid buildup), or yellow staining of the skin.
Sea buckthorn may increase the risk of bleeding. Caution is advised in people with bleeding disorders or those taking drugs that may increase the risk of bleeding. Dosing adjustments may be needed.
Sea buckthorn may lower blood sugar levels. Caution is advised in people with diabetes or low blood sugar, and in those taking drugs, herbs, or supplements that affect blood sugar. Blood sugar levels may need to be monitored by a qualified healthcare professional, including a pharmacist, and medication adjustments may be necessary.
Sea buckthorn may cause low blood pressure. Caution is advised in people with low blood pressure or in those taking drugs or herbs and supplements that lower blood pressure.
Use cautiously in people who are taking agents that affect the immune system, agents that regulate heart rate, agents that treat disorders of the stomach or intestines, anticancer agents (specifically cyclophosphamide or epirubicin (farmorubicin)), and antigout agents.
Use cautiously in people who perform rigorous activity or exercise, or those who have autoimmune diseases or heart rhythm disorders.
Use cautiously when applying sea buckthorn to the skin.
Avoid using doses higher than normal food amounts in children and in pregnant or breastfeeding women.
Avoid in people with known allergy or sensitivity to sea buckthorn, its parts, or other members of the Elaeagnaceae family.

Pregnancy and Breastfeeding

There is a lack of scientific evidence on the use of sea buckthorn during pregnancy or breastfeeding. Avoid using doses higher than normal food amounts in pregnant or breastfeeding women.

dosing

Adults (over 18 years old)

The following forms and doses of sea buckthorn have been taken by mouth: 1-2 cups of sea buckthorn leaf tea, daily; 1-3 seed oil capsules (500 milligrams per capsule), three times daily; 3-5 milliliters of sea buckthorn seed oil, three times daily; up to two "dropperfuls" of sea buckthorn berry oil, three times daily. Sea buckthorn berry or seed oil have also been applied to the skin 3-4 times daily.
For antioxidant effects, sea buckthorn juice has been taken by mouth for eight weeks, although the amount taken was unclear.
For atopic dermatitis (itchy, scaly skin), 10 capsules containing 500 milligrams of sea buckthorn pulp oil have been taken by mouth daily for four months. Creams containing 10-20% sea buckthorn have been applied to the skin for four weeks.
For heart disease, 10 milligrams of sea buckthorn has been taken by mouth three times daily for three months.
For cirrhosis (scarring of the liver caused by chronic disease), 15 grams of sea buckthorn extract has been taken by mouth three times daily for six months.
For dry eyes, two grams of sea buckthorn oil has been taken by mouth for three months.
For weight loss, 100 grams of fresh sea buckthorn berries have been taken by mouth daily for 33-35 days.
For burns, sea buckthorn oil dressings have been applied to the skin.

There is no proven safe or effective dose for sea buckthorn in children.

interactions

Interactions with Drugs

Sea buckthorn may increase the risk of bleeding when taken with drugs that increase the risk of bleeding or clotting. Some examples include aspirin, anticoagulants (blood thinners) such as warfarin (Coumadin®) or heparin, antiplatelet drugs such as clopidogrel (Plavix®), and nonsteroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).
Sea buckthorn may lower blood sugar levels. Caution is advised when using other medications that may also lower blood sugar. Patients taking insulin or drugs for diabetes by mouth should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be needed.
Sea buckthorn may cause low blood pressure. Caution is advised in people taking drugs that lower blood pressure.
Sea buckthorn may interfere with the way the body processes certain drugs using the liver's "cytochrome P450" enzyme system. As a result, the levels of these drugs may be altered in the blood, and may cause altered effects or potentially serious adverse reactions. People using any medications should check the package insert, and speak with a qualified healthcare professional, including a pharmacist, about possible interactions.
Sea buckthorn may also interact with agents that affect the immune system, agents that affect the liver, agents that treat heart disorders, agents that treat stomach and intestine disorders, antibiotics, anticancer agents (including cyclophosphamide or epirubicin (farmorubicin)), antigout agents, anti-inflammatory agents, antiulcer agents, antivirals, cholesterol-lowering agents, heart rate-regulating agents, weight loss agents, or wound-healing agents.

Interactions with Herbs and Dietary Supplements

Sea buckthorn may increase the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding or clotting. Many cases of bleeding have been reported with the use of Ginkgo biloba, and fewer cases with garlic and saw palmetto. Many other herbs and supplements may theoretically increase the risk of bleeding, although this has not been proven in most cases.
Sea buckthorn may lower blood sugar levels. Caution is advised when using other herbs or supplements that may also lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.
Sea buckthorn may lower blood pressure. Caution is advised in people taking herbs or supplements that lower blood pressure.
Sea buckthorn may interfere with the way the body processes certain herbs or supplements using the liver's "cytochrome P450" enzyme system. As a result, the levels of other herbs or supplements may be altered in the blood. It may also alter the effects that other herbs or supplements possibly have on the P450 system.
Sea buckthorn may also interact with antibacterials, anticancer herbs and supplements, antigout herbs and supplements, anti-inflammatory herbs and supplements, antioxidants, antivirals, cholesterol-lowering herbs and supplements, fatty acids, heart rate-regulating herbs and supplements, herbs and supplements that affect the immune system, herbs and supplements that treat heart disorders, herbs and supplements that treat liver disorders, herbs and supplements that treat stomach and intestine disorders, herbs and supplements that treat ulcers, weight loss herbs and supplements, or wound-healing herbs and supplements.