Reflexology involves the application of manual pressure to specific points or areas of the feet that are believed to correspond to other parts of the body. Reflexology is often used with the intention to relieve stress or prevent/treat physical disorders. Pressure may also be applied to the hands or ears.

Techniques similar to reflexology have existed for thousands of years, and were used by ancient Egyptians and early Chinese. In the early 20th century, an American ear, nose, and throat physician, William Fitzgerald, MD, suggested that the foot could be "mapped" to other areas of the body in order to diagnose and treat medical conditions. He divided the body into 10 zones and labeled sections of the foot he believed to control each zone. Dr. Fitzgerald suggested that gentle pressure on a particular area of the foot could generate relief in the targeted zone. This process was originally named zone therapy.

In the 1930s, Eunice Ingham, a nurse and physiotherapist, further developed these maps to include specific reflex points. At this time, the name zone therapy was changed to reflexology. Modern reflexologists in the United States often learn Ingham's method or a similar technique developed by the reflexologist Laura Norman.

Reflexology charts consist of pictures of the soles of the feet on which diagrams of corresponding internal organs or parts of the body are drawn. For example, charts may display that the toes correspond to the head and neck, the ball of the foot to the chest and lungs, the arch of the foot to the internal organs, the heel to the sciatic nerve and pelvic area, and the bone along the arch of the foot to the spine. The right side of the body is believed to be reflected in the right foot, and the left side in the left foot. Although most reflexologists formally claim that these relationships are not used to diagnose disease, practicing reflexologists sometimes assert that tenderness or a gritty feeling of the feet represents current or past disease in the corresponding area of the body. Reflexology is sometimes combined with other techniques, and may be used by healthcare practitioners of various disciplines (such as massage therapists, chiropractors, podiatrists, physical therapists, or nurses).

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Note: The term "reflexotherapy" has been used to describe acupuncture in some countries.