Maitake is the Japanese name for the edible fungus Grifola frondosa, which is characterized by a large fruiting body and overlapping caps. Maitake has been used traditionally both as a food and for medicinal purposes. Polysaccharide constituents of maitake have been associated with multiple bioactive properties in animal studies. Extracts of maitake mushroom, and particularly the beta-glucan polysaccharide constituent, have been associated with immune modulation in pre-clinical studies and are hypothesized to exert anti-tumor effects as a result of their immune properties. Human data are limited and at this time, there is insufficient evidence to recommend for or against the use of oral maitake for any indication.
Beta-glucan, cloud mushroom, dancing mushroom, grifolan, Grifron Pro Maitake D-Fraction Extract®, king of mushroom, Maitake Gold 404®, MDF, MD-fraction, My-take.
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Early studies in the laboratory as well as in humans suggest that beta-glucan extracts from maitake may increase the body's ability to fight cancer. However, these studies have not been well designed and better research is needed before the use of maitake for cancer can be recommended.
In animal studies, maitake extracts are reported to lower blood sugar levels. However, little is known about the effect of maitake on blood sugar in humans.
Animal and laboratory studies suggest that beta-glucan extracts from maitake may alter the immune system. However, no reliable studies in humans are available.